BDBM50140320 2-[4-(2-Oxo-cyclopentylmethyl)-phenyl]-propionic acid::CHEMBL19299::Loxoprofen

SMILES CC(C(O)=O)c1ccc(CC2CCCC2=O)cc1

InChI Key InChIKey=YMBXTVYHTMGZDW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50140320   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50140320(2-[4-(2-Oxo-cyclopentylmethyl)-phenyl]-propionic a...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibitory potency against Prostaglandin G/H synthase 1 in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50140320(2-[4-(2-Oxo-cyclopentylmethyl)-phenyl]-propionic a...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50140320(2-[4-(2-Oxo-cyclopentylmethyl)-phenyl]-propionic a...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against recombinant human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50140320(2-[4-(2-Oxo-cyclopentylmethyl)-phenyl]-propionic a...)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibitory potency against cyclooxygenase-2 in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed