BDBM50140727 5-(3,4-dichlorophenyl)-3-phenyl-(3R,3aR,6aS)-spiro[perhydrofuro[3,4-c]pyrrole-1,2'-(2',3'-dihydro-1'H-indene)]-1',3',4,6-tetraone::CHEMBL27258

SMILES Oc1c2[C@@H](OC3(C(=O)c4ccccc4C3=O)c2c(O)n1-c1ccc(Cl)c(Cl)c1)c1ccccc1

InChI Key InChIKey=XWFFZCFXZJOHJE-NRFANRHFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140727   

TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140727(5-(3,4-dichlorophenyl)-3-phenyl-(3R,3aR,6aS)-spiro...)
Affinity DataIC50:  5.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Staphylococcus aureus phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase, mitochondrial(Homo sapiens (Human))
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140727(5-(3,4-dichlorophenyl)-3-phenyl-(3R,3aR,6aS)-spiro...)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Escherichia coli phenylalanyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed