BDBM50142517 CHEMBL47885::N-[4-(3,4,5-triihydroxy-benzoylamino)-phenyl]-3,4,5-trihydroxy-benzamide

SMILES Oc1cc(cc(O)c1O)C(=O)Nc1ccc(NC(=O)c2cc(O)c(O)c(O)c2)cc1

InChI Key InChIKey=HJGFIANFXKLTIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142517   

TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142517(CHEMBL47885 | N-[4-(3,4,5-triihydroxy-benzoylamino...)
Affinity DataIC50:  150nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase II by detecting the conversion of supercoiled pBR322 DNA to its relaxed for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50142517(CHEMBL47885 | N-[4-(3,4,5-triihydroxy-benzoylamino...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed formMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed