BDBM50143600 CHEBI:29571::Dehydroabietic Acid

SMILES [H][C@@]12CCc3cc(ccc3[C@@]1(C)CCC[C@@]2(C)C(O)=O)C(C)C

InChI Key InChIKey=NFWKVWVWBFBAOV-MISYRCLQSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50143600   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50143600(CHEBI:29571 | Dehydroabietic Acid)
Affinity DataIC50:  3.63E+4nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged full length human Cdk2/human recombinant N-terminal GST-tagged full-length Cyclin E using hist...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50143600(CHEBI:29571 | Dehydroabietic Acid)
Affinity DataEC50:  4.20E+4nMAssay Description:Transactivation of human Gal4-fused RXRalpha LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50143600(CHEBI:29571 | Dehydroabietic Acid)
Affinity DataIC50: >100nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50143600(CHEBI:29571 | Dehydroabietic Acid)
Affinity DataEC50:  4.20E+4nMAssay Description:Transactivation of human Gal4-fused RXRgamma LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50143600(CHEBI:29571 | Dehydroabietic Acid)
Affinity DataIC50:  28nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50143600(CHEBI:29571 | Dehydroabietic Acid)
Affinity DataEC50:  4.20E+4nMAssay Description:Transactivation of human Gal4-fused RXRbeta LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed