BDBM50143731 (2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-methoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::CHEMBL57644

SMILES COc1ccc(cc1)S(=O)(=O)N1C[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1C(=O)NO

InChI Key InChIKey=SSQXFNKOLMHXPO-DDHJBXDOSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50143731   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50143731((2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-methoxy-benzen...)
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant matrix metalloprotease 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50143731((2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-methoxy-benzen...)
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant matrix metalloprotease 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50143731((2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-methoxy-benzen...)
Affinity DataKi:  15nMAssay Description:Inhibition of human tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50143731((2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-methoxy-benzen...)
Affinity DataKi:  26nMAssay Description:Inhibition of human recombinant matrix metalloprotease 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50143731((2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-methoxy-benzen...)
Affinity DataIC50:  450nMAssay Description:Inhibition of heparin-binding HB-EGF sheddingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed