BDBM50143868 3-{[3-(4-Carbamimidoyl-phenyl)-1-methyl-2,4-dioxo-1,3,8-triaza-spiro[4.5]decane-8-carbonyl]-amino}-3-phenyl-propionic acid::CHEMBL63500

SMILES CN1C(=O)N(C(=O)C11CCN(CC1)C(=O)NC(CC(O)=O)c1ccccc1)c1ccc(cc1)C(N)=N

InChI Key InChIKey=MVQSMJLSSPOGKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143868   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143868(3-{[3-(4-Carbamimidoyl-phenyl)-1-methyl-2,4-dioxo-...)
Affinity DataIC50:  103nMAssay Description:Inhibition of platelet aggregation induced by 20 microM adenosine 5-diphosphate (ADP) in citrated human platelet rich plasma (h-PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143868(3-{[3-(4-Carbamimidoyl-phenyl)-1-methyl-2,4-dioxo-...)
Affinity DataIC50:  50nMAssay Description:Tested for inhibition of the binding of fibrinogen to purified human GPIIb-IIIa in a 96-well format (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed