BDBM50143874 (R)-3-{[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-spiro[4.5]decane-8-carbonyl]-amino}-butyric acid::CHEMBL65420

SMILES C[C@H](CC(O)=O)NC(=O)N1CCC2(CCN(C2=O)c2ccc(cc2)C(N)=N)CC1

InChI Key InChIKey=MQWGOPKAWPNVQO-CYBMUJFWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143874   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143874((R)-3-{[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza...)
Affinity DataIC50:  68nMAssay Description:Inhibition of platelet aggregation induced by 20 microM adenosine 5-diphosphate (ADP) in citrated human platelet rich plasma (h-PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143874((R)-3-{[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza...)
Affinity DataIC50:  5nMAssay Description:Tested for inhibition of the binding of fibrinogen to purified human GPIIb-IIIa in a 96-well format (ELISA assay)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed