BDBM50144555 (R)-1-{4-[2-(4-Benzyloxy-phenyl)-acetyl]-piperazine-1-carbonyl}-4-oxo-3-piperidin-4-ylmethyl-azetidine-2-carboxylic acid::CHEMBL69394

SMILES OC(=O)[C@@H]1[C@@H](CC2CCNCC2)C(=O)N1C(=O)N1CCN(CC1)C(=O)Cc1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=FYVVIEIXYWNGDL-VPUSJEBWSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50144555   

TargetSerine protease 1(Bos taurus (bovine))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144555((R)-1-{4-[2-(4-Benzyloxy-phenyl)-acetyl]-piperazin...)
Affinity DataIC50:  440nMAssay Description:Inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144555((R)-1-{4-[2-(4-Benzyloxy-phenyl)-acetyl]-piperazin...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against human tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144555((R)-1-{4-[2-(4-Benzyloxy-phenyl)-acetyl]-piperazin...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory activity against tissue type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144555((R)-1-{4-[2-(4-Benzyloxy-phenyl)-acetyl]-piperazin...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibitory activity against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144555((R)-1-{4-[2-(4-Benzyloxy-phenyl)-acetyl]-piperazin...)
Affinity DataIC50:  380nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144555((R)-1-{4-[2-(4-Benzyloxy-phenyl)-acetyl]-piperazin...)
Affinity DataIC50:  440nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed