BDBM50144892 CHEMBL3764398

SMILES CCC(Cc1ccc(cc1)C(=O)NCc1ccc(OC)cc1C(F)(F)F)C(O)=O

InChI Key InChIKey=VPAHYLNIDWFBPW-UHFFFAOYSA-N

Data  2 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50144892   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50144892(CHEMBL3764398)
Affinity DataEC50:  300nMAssay Description:Transactivation of human PPARgamma expressed in African green monkey COS7 cells incubated overnight by dual-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50144892(CHEMBL3764398)
Affinity DataEC50:  390nMAssay Description:Agonist activity at human GAL4 DBD-fused PPARgamma LBD (203 to 505 residues) transfected in HEK293T cells assessed as fold activation incubated for 1...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50144892(CHEMBL3764398)
Affinity DataIC50:  300nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL
LigandPNGBDBM50144892(CHEMBL3764398)
Affinity DataIC50:  330nMAssay Description:Inhibition of human recombinant sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition measured for 30 mins by fluoresc...More data for this Ligand-Target Pair