BDBM50145154 CHEMBL3764920
SMILES Fc1ccc(cc1)[C@@H]1[C@H](Nc2cccc3c2c1n[nH]c3=O)c1ccc(CN2CCC2)cc1
InChI Key InChIKey=UMTZOWPWZLHANK-ISKFKSNPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50145154
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 6.30nMAssay Description:Inhibition of PARP in human LoVo cells assessed as inhibition of poly(ADP)-ribose polymerization for 30 mins by fluorescence assayMore data for this Ligand-Target Pair