BDBM50145689 CHEMBL80844::[1-[(S)-2-((R)-2-Benzyloxycarbonylamino-3-hydroxy-propionylamino)-propionylamino]-2-(4-guanidino-phenyl)-ethyl]-phosphonic acid diphenyl ester::diphenyl 1-[(N-benzoyloxycarbonyl-D-seryl)-L-alanyl]amino-2-(4-guanidinophenyl)ethanephosphonate

SMILES [#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-[#8])-[#7]-[#6](=O)-[#8]-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](/[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1

InChI Key InChIKey=GYFYCGMUNLSJCM-XPKRSZDKSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50145689   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50145689(CHEMBL80844 | [1-[(S)-2-((R)-2-Benzyloxycarbonylam...)
Affinity DataIC50:  57nMAssay Description:Inhibitory activity of the compound was tested against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50145689(CHEMBL80844 | [1-[(S)-2-((R)-2-Benzyloxycarbonylam...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity of the compound was tested against Tissue type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50145689(CHEMBL80844 | [1-[(S)-2-((R)-2-Benzyloxycarbonylam...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity of the compound was tested against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50145689(CHEMBL80844 | [1-[(S)-2-((R)-2-Benzyloxycarbonylam...)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibitory activity of the compound was tested against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50145689(CHEMBL80844 | [1-[(S)-2-((R)-2-Benzyloxycarbonylam...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50145689(CHEMBL80844 | [1-[(S)-2-((R)-2-Benzyloxycarbonylam...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50145689(CHEMBL80844 | [1-[(S)-2-((R)-2-Benzyloxycarbonylam...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50145689(CHEMBL80844 | [1-[(S)-2-((R)-2-Benzyloxycarbonylam...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of recombinant tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University Of Antwerp

Curated by ChEMBL
LigandPNGBDBM50145689(CHEMBL80844 | [1-[(S)-2-((R)-2-Benzyloxycarbonylam...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibitory activity of the compound was tested against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed