BDBM50145709 (Z)-3-(2,5-Dimethoxy-phenyl)-2-(4-methoxy-phenyl)-acrylonitrile::3-(2,5-dimethoxyphenyl)-2-(4-methoxyphenyl)acrylonitrile::CHEMBL81228

SMILES COc1ccc(cc1)C(=C\c1cc(OC)ccc1OC)\C#N

InChI Key InChIKey=HIZRJOUYMUFYHL-XNTDXEJSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50145709   

TargetSortase family protein(Staphylococcus aureus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50145709((Z)-3-(2,5-Dimethoxy-phenyl)-2-(4-methoxy-phenyl)-...)
Affinity DataIC50:  9.24E+3nMAssay Description:Inhibitory activity towards SrtA (sortase A)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSortase family protein(Staphylococcus aureus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50145709((Z)-3-(2,5-Dimethoxy-phenyl)-2-(4-methoxy-phenyl)-...)
Affinity DataIC50:  9.24E+3nMAssay Description:Inhibition of precipitation of human soluble CD69 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSortase family protein(Staphylococcus aureus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50145709((Z)-3-(2,5-Dimethoxy-phenyl)-2-(4-methoxy-phenyl)-...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of 6-His tagged Staphylococcus aureus recombinant sortase delta N24 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed