BDBM50145794 4-[5-(2,4-Diamino-pteridin-6-ylmethyl)-5H-dibenzo[b,f]azepin-2-yloxymethyl]-benzoic acid::CHEMBL79464
SMILES Nc1nc(N)c2nc(CN3c4ccccc4C=Cc4cc(OCc5ccc(cc5)C(O)=O)ccc34)cnc2n1
InChI Key InChIKey=GMQTWPBHDPZEKG-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50145794
Affinity DataIC50: 580nMAssay Description:Concentration required to inhibit the rat liver Dihydrofolate reductase by 50% was determined; Range : 500-680More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Concentration required to inhibit the Toxoplasma gondii Dihydrofolate reductase by 50% was determined; Range : 18-27More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Concentration required to inhibit the Pneumocystis carinii Dihydrofolate reductase by 50% was determined; Range : 0.88-1.2More data for this Ligand-Target Pair
Affinity DataIC50: 0.75nMAssay Description:Concentration required to inhibit the Mycobacterium avium Dihydrofolate reductase by 50% was determined; Range : 0.55-1.0More data for this Ligand-Target Pair