BDBM50146357 CHEMBL329268::Dimethyl-[(2S,3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-amine

SMILES CN(C)C[C@@H]1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21

InChI Key InChIKey=ACTVOFFLDWZANE-PWIZWCRZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50146357   

TargetHistamine H1 receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146357(CHEMBL329268 | Dimethyl-[(2S,3aR,12bS)-1-(3,3a,8,1...)
Affinity DataKi:  0.630nMAssay Description:Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146357(CHEMBL329268 | Dimethyl-[(2S,3aR,12bS)-1-(3,3a,8,1...)
Affinity DataKi:  3.30nMAssay Description:Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146357(CHEMBL329268 | Dimethyl-[(2S,3aR,12bS)-1-(3,3a,8,1...)
Affinity DataKi:  20nMAssay Description:Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed