BDBM50146453 (E)-3-(4-Methoxy-phenyl)-acrylic acid::3-(4-methoxyphenyl)acrylic acid::4-Methoxycinnamic acid::CHEMBL95770::para-methoxycinnamic acid

SMILES COc1ccc(\C=C\C(O)=O)cc1

InChI Key InChIKey=AFDXODALSZRGIH-QPJJXVBHSA-N

Data  10 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50146453   

TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453((E)-3-(4-Methoxy-phenyl)-acrylic acid | 3-(4-metho...)
Affinity DataIC50:  4.10E+5nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453((E)-3-(4-Methoxy-phenyl)-acrylic acid | 3-(4-metho...)
Affinity DataIC50:  4.10E+5nMAssay Description:Inhibition of mushroom tyrosinase assessed as 3,4-dihydroxy-L-phenylalanine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453((E)-3-(4-Methoxy-phenyl)-acrylic acid | 3-(4-metho...)
Affinity DataIC50:  4.10E+5nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453((E)-3-(4-Methoxy-phenyl)-acrylic acid | 3-(4-metho...)
Affinity DataIC50: >3.50E+5nMAssay Description:Inhibition of mushroom tyrosinase after 25 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-glucosidase MAL62(Saccharomyces cerevisiae)TBA
LigandPNGBDBM50146453((E)-3-(4-Methoxy-phenyl)-acrylic acid | 3-(4-metho...)
Affinity DataIC50:  4.00E+10nMAssay Description:Inhibition of baker's yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453((E)-3-(4-Methoxy-phenyl)-acrylic acid | 3-(4-metho...)
Affinity DataIC50:  4.10E+5nMAssay Description:Inhibition of mashroom tyrosinase assessed as oxidation of L-DOPA by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453((E)-3-(4-Methoxy-phenyl)-acrylic acid | 3-(4-metho...)
Affinity DataIC50:  4.10E+5nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146453((E)-3-(4-Methoxy-phenyl)-acrylic acid | 3-(4-metho...)
Affinity DataIC50:  7.60E+5nMAssay Description:Binding affinity towards HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146453((E)-3-(4-Methoxy-phenyl)-acrylic acid | 3-(4-metho...)
Affinity DataIC50:  8.50E+5nMAssay Description:Binding affinity towards HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50146453((E)-3-(4-Methoxy-phenyl)-acrylic acid | 3-(4-metho...)
Affinity DataIC50:  4.10E+5nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectropho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed