BDBM50146460 CHEMBL3763688

SMILES Cl.NOCc1ccc(I)cc1

InChI Key InChIKey=QKTGWFUBZHRJRK-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50146460   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146460(CHEMBL3763688)
Affinity DataKi:  164nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by Michaelis-Menton...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146460(CHEMBL3763688)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146460(CHEMBL3763688)
Affinity DataIC50:  82nMAssay Description:Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 5-fold serial dilution beginning...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146460(CHEMBL3763688)
Affinity DataIC50:  210nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reade...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146460(CHEMBL3763688)
Affinity DataIC50:  95nMAssay Description:Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 3-fold serial dilution beginning...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatalase(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146460(CHEMBL3763688)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of catalase (unknown origin) using hydrogen peroxide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146460(CHEMBL3763688)
Affinity DataIC50:  180nMAssay Description:Inhibition of doxycycline-induced human IDO1 expressed in Trex cells assessed as reduction in kynurenine production treated with 5-fold serial diluti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed