BDBM50146461 CHEMBL3765807

SMILES Cl.NOCc1cccc(Cl)c1

InChI Key InChIKey=PZPCEIVCWGWHCC-UHFFFAOYSA-N

Data  2 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50146461   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataKi:  154nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by Michaelis-Menton...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlanine--glyoxylate aminotransferase(Homo sapiens)
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of recombinant wild type His-tagged AGT (unknown origin) expressed in Escherichia coli BL21 assessed as inhibition constant using L-alanin...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50:  114nMAssay Description:Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 5-fold serial dilution beginning...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50:  77nMAssay Description:Inhibition of doxycycline-induced human IDO1 expressed in Trex cells assessed as reduction in kynurenine production treated with 5-fold serial diluti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50:  134nMAssay Description:Inhibition of IFN gamma induced human IDO1 in HeLa cells assessed as reduction in kynurenine production treated with 3-fold serial dilution beginning...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reade...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlanine--glyoxylate aminotransferase(Homo sapiens)
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50:  700nMAssay Description:Inhibition of recombinant wild type His-tagged AGT (unknown origin) expressed in Escherichia coli BL21 using L-alanine and glyoxylate as a substrate ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCatalase(Homo sapiens (Human))
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50146461(CHEMBL3765807)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of catalase (unknown origin) using hydrogen peroxide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed