BDBM50146472 CHEMBL318252::N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide::N-hydroxy-N-(1-(1-isobutylpiperidin-4-ylidene)-3-(4-((2-methylquinolin-4-yl)methoxy)phenylsulfonyl)propan-2-yl)formamide

SMILES [#6]-[#6](-[#6])-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]/[#6](-[#6]S(=O)(=O)c1ccc(-[#8]-[#6]-c2cc(-[#6])nc3ccccc23)cc1)-[#7](-[#8])-[#6]=O

InChI Key InChIKey=ODPDWLUYVWCNHO-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50146472   

TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50:  6nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50146472(CHEMBL318252 | N-Hydroxy-N-{1-(1-isobutyl-piperidi...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed