BDBM50146511 4-{(E)-3-[4-((3R,3aS)-7,8-Dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-3-ylmethyl)-piperazin-1-yl]-1-methyl-propenyl}-phenol::CHEMBL329065

SMILES COc1cc2OC[C@H]3[C@H](CN4CCN(C\C=C(/C)c5ccc(O)cc5)CC4)ON=C3c2cc1OC

InChI Key InChIKey=VMLJCXYBTLCGDU-FHYDSMICSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50146511   

TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146511(4-{(E)-3-[4-((3R,3aS)-7,8-Dimethoxy-3a,4-dihydro-3...)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity to human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146511(4-{(E)-3-[4-((3R,3aS)-7,8-Dimethoxy-3a,4-dihydro-3...)
Affinity DataKi:  1.90nMAssay Description:In vitro binding affinity to the human alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146511(4-{(E)-3-[4-((3R,3aS)-7,8-Dimethoxy-3a,4-dihydro-3...)
Affinity DataKi:  7.60nMAssay Description:In vitro binding affinity towards human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed