BDBM50146899 4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2-ylmethoxy)-quinolin-8-yloxymethyl]-phenyl}-methyl-carbamoyl)-methyl]-carbamoyl}-vinyl)-N-methyl-benzamide::CHEMBL99869

SMILES CNC(=O)c1ccc(\C=C\C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(OCc5ccccn5)cc(C)nc34)c2Cl)cc1

InChI Key InChIKey=YFMDLMSUZMRKKH-SFQUDFHCSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146899   

TargetB2 bradykinin receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50146899(4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50146899(4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2...)
Affinity DataIC50:  0.410nMAssay Description:Agonist activity at bradykinin B2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50146899(4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of [3H]BK (1.0 nM) binding to the human bradykinin receptor B2, expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50146899(4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2...)
Affinity DataIC50:  2.30nMAssay Description:Concentration required to inhibit specific binding of [3H]-BK(0.06 nM) to the bradykinin receptor B2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed