BDBM50147620 CHEMBL3769507

SMILES CCn1cc(-c2cccc(c2)C(F)(F)F)c2sc(cc2c1=O)C(=N)NC1CCS(=O)(=O)CC1

InChI Key InChIKey=WRUWGLUCNBMGPS-UHFFFAOYSA-N

Data  1 KI  5 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50147620   

TargetBromodomain-containing protein 9(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50147620(CHEMBL3769507)
Affinity DataKi:  2nMAssay Description:Binding affinity to human partial length BRD9 (R130 to V259 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 7(Homo sapiens (Human))
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50147620(CHEMBL3769507)
Affinity DataKd:  148nMAssay Description:Binding affinity to recombinant human His-tagged BRD7 (129 to 250 residues) expressed in Escherichia coli BL21 DE3 assessed as dissociation constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 7(Homo sapiens (Human))
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50147620(CHEMBL3769507)
Affinity DataKd:  398nMAssay Description:Binding affinity to BRD7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 9(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50147620(CHEMBL3769507)
Affinity DataKd:  2nMAssay Description:Binding affinity to BRD9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 9(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50147620(CHEMBL3769507)
Affinity DataIC50:  10nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) incubated in dark for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 9(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50147620(CHEMBL3769507)
Affinity DataKd:  37nMAssay Description:Binding affinity to recombinant human His-tagged BRD9 (134 to 239 residues) expressed in Escherichia coli BL21 DE3 assessed as dissociation constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeregrin(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50147620(CHEMBL3769507)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of BRD9 in human HUT78 cells incubated for 45 mins by chemoproteomic competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChromatin remodeling regulator CECR2(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50147620(CHEMBL3769507)
Affinity DataIC50:  196nMAssay Description:Inhibition of BRD3 in human HUT78 cells incubated for 45 mins by chemoproteomic competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50147620(CHEMBL3769507)
Affinity DataIC50:  3.05E+3nMAssay Description:Binding affinity to partial length human BRD7 by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50147620(CHEMBL3769507)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) incubated in dark for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed