BDBM50148037 CHEMBL3764561

SMILES CC(C)n1cnc2c(NCCCCCCC(=O)NO)nc(N)nc12

InChI Key InChIKey=BNYGJTCBUVSIDI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148037   

TargetHistone deacetylase 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50148037(CHEMBL3764561)
Affinity DataIC50:  154nMAssay Description:Inhibition of C-terminal GST-tagged human recombinant HDAC2 expressed in Sf9 cells after 30 mins by microtiter plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50148037(CHEMBL3764561)
Affinity DataIC50:  30nMAssay Description:Inhibition of HDAC1/2 in human HeLa cell nuclear extract using color de Lys as substrate preincubated for 5 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50148037(CHEMBL3764561)
Affinity DataIC50:  3.13E+3nMAssay Description:Inhibition of C-terminal His-tagged human recombinant HDAC8 expressed in Sf9 cells after 30 mins by microtiter plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed