BDBM50148171 4-(Pyridin-2-ylamino)-piperidine-1-carboxylic acid ethyl ester::CHEMBL112247::ethyl 4-(pyridin-2-ylamino)piperidine-1-carboxylate

SMILES CCOC(=O)N1CCC(CC1)Nc1ccccn1

InChI Key InChIKey=LIKFZBWZGQWAMR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148171   

TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148171(4-(Pyridin-2-ylamino)-piperidine-1-carboxylic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148171(4-(Pyridin-2-ylamino)-piperidine-1-carboxylic acid...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of iNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148171(4-(Pyridin-2-ylamino)-piperidine-1-carboxylic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148171(4-(Pyridin-2-ylamino)-piperidine-1-carboxylic acid...)
Affinity DataIC50:  1.30E+4nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed