BDBM50148172 CHEMBL251949::KYS-05042::N-(4-(4-fluorophenylsulfonamido)benzyl)-2-(3-phenyl-2-(piperidin-1-yl)-3,4-dihydroquinazolin-4-yl)acetamide::N-[4-(4-Fluoro-benzenesulfonylamino)-benzyl]-2-(3-phenyl-2-piperidin-1-yl-3,4-dihydro-quinazolin-4-yl)-acetamide

SMILES Fc1ccc(cc1)S(=O)(=O)Nc1ccc(CNC(=O)CC2N(C(=Nc3ccccc23)N2CCCCC2)c2ccccc2)cc1

InChI Key InChIKey=RMQZAKOLGVUVAD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148172   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50148172(CHEMBL251949 | KYS-05042 | N-(4-(4-fluorophenylsul...)
Affinity DataIC50:  200nMAssay Description:Concentration of the compounds required for inhibition of HEK293 cells (alpha1G T-type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50148172(CHEMBL251949 | KYS-05042 | N-(4-(4-fluorophenylsul...)
Affinity DataIC50:  110nMAssay Description:Inhibition of T-type [Ca2+] channel (alpha1G) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50148172(CHEMBL251949 | KYS-05042 | N-(4-(4-fluorophenylsul...)
Affinity DataIC50:  110nMAssay Description:Inhibition of T-type calcium channel Cav3.1 alpha1G expressed in HEK293 cells by whole cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50148172(CHEMBL251949 | KYS-05042 | N-(4-(4-fluorophenylsul...)
Affinity DataIC50:  200nMAssay Description:Inhibition of alpha1G T-type calcium channel expressed in HEK293 cells by electrophysiological methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed