BDBM50148269 CHEMBL3770219
SMILES Cc1nn(C)c(C)c1Cc1nnc(o1)-c1cc(Cl)ccc1OC1CCNCC1
InChI Key InChIKey=AYWNZLSZEHOECC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50148269
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Inhibition of human NMT1 R295Q/W297F/A452M/L453V/L462V/N473H/L495M/Q496L mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as subst...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity to human N-myristoyltransferase by fluorescence analysisMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase(Leishmania major)
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition of N-terminal TEV cleavage site-fused His6 tagged Leishmania major NMT (11 to 421 residues) expressed in Escherichia coli Rosetta-2 cells ...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Inhibition of human NMT1 L495M mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA after 30 mins b...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Inhibition of human NMT1 N473H/L495M/Q496L mutant expressed in Escherichia coli Rosetta-2 cells using GSNKSKPK as substrate in presence of MyrCoA aft...More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Johannes Gutenberg-Universit£T Mainz
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibition of N-terminal TEV cleavage site-fused His6 tagged human NMT1 (115 to 496 residues) expressed in Escherichia coli Rosetta-2 cells using GSN...More data for this Ligand-Target Pair