BDBM50148324 2-(4-Chloro-phenyl)-2,5a,6,7,8,8a-hexahydro-5H-cyclopenta[b]pyrazolo[3,4-d]pyridin-3-one::CHEMBL117874

SMILES Clc1ccc(cc1)-n1[nH]c2C3CCCC3N=Cc2c1=O

InChI Key InChIKey=GSLDBWNPXFIQAV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148324   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148324(2-(4-Chloro-phenyl)-2,5a,6,7,8,8a-hexahydro-5H-cyc...)
Affinity DataKi:  0.440nMAssay Description:In vitro binding affinity against gamma-aminobutyric acid A receptor, alpha 1 expressed in L(tk) cells by displacement of [3H]-Ro-15-1788More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148324(2-(4-Chloro-phenyl)-2,5a,6,7,8,8a-hexahydro-5H-cyc...)
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity against Gamma-aminobutyric acid A receptor, alpha 3 expressed in L(tk) cells by displacement of [3H]-Ro-15-1788More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed