BDBM50148628 CHEMBL3769629

SMILES [H][C@]12CCCN1C(=O)[C@]1([H])CCCN1C(=O)C[C@@H](NC(=O)[C@@H](NC2=O)C(C)C)C(=O)NCCCC(=O)NO

InChI Key InChIKey=KEGNHRHLBGEVRZ-JEWRLFTDSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50148628   

TargetHistone deacetylase 3(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50148628(CHEMBL3769629)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant human KDAC3 using FITC-p53 acetylated peptide substrate incubated for 60 mins by microfluidic chip-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50148628(CHEMBL3769629)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant human KDAC1 using FAM-labelled substrate A incubated for 60 mins by microfluidic chip-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Washington University

Curated by ChEMBL
LigandPNGBDBM50148628(CHEMBL3769629)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50148628(CHEMBL3769629)
Affinity DataIC50:  7.66E+3nMAssay Description:Inhibition of recombinant human KDAC6 using FITC-histone 4 acetylated peptide substrate incubated for 60 mins by microfluidic chip-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50148628(CHEMBL3769629)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant human KDAC8 using FAM-labelled substrate B incubated for 60 mins by microfluidic chip-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed