BDBM50148729 CHEMBL3770923::US9518026, Example 66::US9956214, Compound 1565
SMILES CC(C)(C)n1nc(c(C(N)=O)c1N)-c1cnc2cc(OC(F)(F)F)ccc2c1
InChI Key InChIKey=YJMHWCFTOAMRPN-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50148729
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of Toxoplasma gondii CDPK1 assessed as ATP consumption using (Biotin-C6-PLARTLSVAGLPGKK) as substrate after 90 mins by luciferase reporter...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalcium-dependent protein kinase 1(Cryptosporidium parvum)
University of Washington Through Its Center For Commercialization
US Patent
University of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 38nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetUncharacterized protein(Cryptosporidium parvum)
University of Washington Through Its Center For Commercialization
US Patent
University of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair