BDBM50149693 2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-acetamide::CHEMBL363722

SMILES Fc1ccc(CC2CCN(CC2)C(=O)C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1

InChI Key InChIKey=NNGDRDBKEGGJQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149693   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
I2Bm

Curated by ChEMBL
LigandPNGBDBM50149693(2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]-Ro-256981 from recombinant NR1/NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
I2Bm

Curated by ChEMBL
LigandPNGBDBM50149693(2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed