BDBM50149882 CHEMBL3771083

SMILES CN(C1CCCC1)c1cc(Br)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C

InChI Key InChIKey=FGZCXBRWZHJWBZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149882   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50149882(CHEMBL3771083)
Affinity DataIC50:  30nMAssay Description:Inhibition of methyltransferase activity of human EZH2 using chicken oligonucleotide as substrate by pull down assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50149882(CHEMBL3771083)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of methyltransferase activity of EZH2 in human lymphoma cells assessed as H3K27 methylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM50149882(CHEMBL3771083)
Affinity DataEC50:  500nMAssay Description:Inhibition of methyltransferase activity of EZH2 in human G401 cells assessed as H3K27 trimethylation after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed