BDBM50150103 CHEMBL338520::[2-(6-Chloro-1H-benzoimidazol-4-yloxy)-ethyl]-[3-(5-fluoro-1H-indol-3-yl)-propyl]-amine

SMILES Fc1ccc2[nH]cc(CCCNCCOc3cc(Cl)cc4[nH]cnc34)c2c1

InChI Key InChIKey=WHXNJTORMHZUJH-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150103   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150103(CHEMBL338520 | [2-(6-Chloro-1H-benzoimidazol-4-ylo...)
Affinity DataKi:  0.390nMAssay Description:Binding affinity against serotonin transporter in rat cortical tissues using radioligand [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150103(CHEMBL338520 | [2-(6-Chloro-1H-benzoimidazol-4-ylo...)
Affinity DataKi:  10.7nMAssay Description:Binding affinity against human 5-hydroxytryptamine 1A receptor in CHO cells labeled with [3H]-8-OH-DPAT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150103(CHEMBL338520 | [2-(6-Chloro-1H-benzoimidazol-4-ylo...)
Affinity DataIC50:  238nMAssay Description:Inhibition concentration against 5-hydroxytryptamine 1A receptor using cAMP as radioligand in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150103(CHEMBL338520 | [2-(6-Chloro-1H-benzoimidazol-4-ylo...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition concentration against [3H]-5-HT uptake by human serotonin transporter in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150103(CHEMBL338520 | [2-(6-Chloro-1H-benzoimidazol-4-ylo...)
Affinity DataIC50:  66.5nMAssay Description:Inhibition concentration against binding of radioligand [35]GTPgammaS in CHO cells expressing 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed