BDBM50150157 CHEMBL436002::Carbamic acid (4E,6Z,10E)-(8S,9S,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-19-[4-(4-methyl-piperazin-1-ylmethyl)-benzoylamino]-3,20,22-trioxo-2-aza-bicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl ester
SMILES CO[C@H]1CC(C)=Cc2c(O)c(NC(=O)C(C)=CC=C[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)cc(O)c2NC(=O)c1ccc(CN2CCN(C)CC2)cc1
InChI Key InChIKey=JNDOPIAQDRPTOH-HHIIGDKZSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50150157
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Conforma Therapeutics
Curated by ChEMBL
Conforma Therapeutics
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Concentration of test compound required for half-maximal inhibition of binding of Heat shock 90 KD protein by MCF-7 cell lysate assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Conforma Therapeutics
Curated by ChEMBL
Conforma Therapeutics
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human epidermal growth factor 2 (Her-2) degredation in MCF-7 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Conforma Therapeutics
Curated by ChEMBL
Conforma Therapeutics
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Concentration required to inhibit biotin-GM binding to recombinant heat shock protein 90(rHsp90)More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Conforma Therapeutics
Curated by ChEMBL
Conforma Therapeutics
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Concentration required to inhbit Bis-ANS activity by recombinant heat shock protein 90 (rHSP90) conformational assayMore data for this Ligand-Target Pair