BDBM50151376 CHEMBL3775654

SMILES COc1ccc(cc1OCCCCC(=O)NO)N(C)c1nc(C)nc2ccccc12

InChI Key InChIKey=RSCCJCHEZJEYKQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151376   

TargetHistone deacetylase 1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151376(CHEMBL3775654)
Affinity DataIC50:  253nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151376(CHEMBL3775654)
Affinity DataIC50:  5.19E+3nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151376(CHEMBL3775654)
Affinity DataIC50:  111nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed