BDBM50152294 4-[5-(3,5-difluorophenyl)-4-(3-dipropylcarbamoylphenylcarboxamido)-1-ethyl-3-hydroxypentylcarboxamidomethyl]-1-cyclohexanecarboxylic acid::CHEMBL364406

SMILES CCCN(CCC)C(=O)c1cccc(c1)C(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@@H](O)C[C@@H](CC)C(=O)NC[C@H]1CCC(CC1)C(O)=O

InChI Key InChIKey=YRTFQCVTZROZMF-SZZTTZGWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152294   

TargetBeta-secretase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50152294(4-[5-(3,5-difluorophenyl)-4-(3-dipropylcarbamoylph...)
Affinity DataIC50:  50nMAssay Description:Binding affinity against Beta-secretaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed