BDBM50152510 CHEMBL365696::{2-Methyl-1-[4-(4-methyl-3,4-dihydro-2H-benzo[1,4]oxazin-2-ylmethoxy)-benzoyl]-1H-indol-4-yl}-acetic acid

SMILES CN1C[C@H](COc2ccc(cc2)C(=O)n2c(C)cc3c(CC(O)=O)cccc23)Oc2ccccc12

InChI Key InChIKey=XECAIYOLUPUKEJ-JOCHJYFZSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50152510   

TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152510(CHEMBL365696 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Affinity DataKi:  170nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing human Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152510(CHEMBL365696 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Affinity DataKi:  230nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152510(CHEMBL365696 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Affinity DataKi:  410nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152510(CHEMBL365696 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152510(CHEMBL365696 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152510(CHEMBL365696 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152510(CHEMBL365696 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Affinity DataIC50:  10nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed