BDBM50152685 CHEMBL3780676

SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(Cl)c5ccccc5n(-c5ccc(F)cc5)c4=O)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=HBQMROYUNHRFSB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50152685   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Jiangxi Science And Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50152685(CHEMBL3780676)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Jiangxi Science And Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50152685(CHEMBL3780676)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of FLT3 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangxi Science And Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50152685(CHEMBL3780676)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Jiangxi Science And Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50152685(CHEMBL3780676)
Affinity DataIC50:  527nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Jiangxi Science And Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50152685(CHEMBL3780676)
Affinity DataIC50:  543nMAssay Description:Inhibition of VEGFR-2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Jiangxi Science And Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50152685(CHEMBL3780676)
Affinity DataIC50:  363nMAssay Description:Inhibition of cKIT (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed