BDBM50152989 3-(5-carbamoyl-3-(4-iodophenyl)-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-1-yl)-1-(4-(2-cyanophenyl)piperazin-1-yl)propan-2-yl carbamate::CHEMBL178194::Carbamic acid 1-[5-carbamoyl-3-(4-iodo-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-ylmethyl]-2-[4-(2-cyano-phenyl)-piperazin-1-yl]-ethyl ester::Carbamic acid 2-[5-carbamoyl-3-(4-iodo-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-1-[4-(2-cyano-phenyl)-piperazin-1-ylmethyl]-ethyl ester

SMILES NC(=O)OC(CN1CCN(CC1)c1ccccc1C#N)Cn1nc(c2CN(CCc12)C(N)=O)-c1ccc(I)cc1

InChI Key InChIKey=OPNPKOZGYIOUCH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50152989   

TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50152989(3-(5-carbamoyl-3-(4-iodophenyl)-4,5,6,7-tetrahydro...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against human cysteine protease cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50152989(3-(5-carbamoyl-3-(4-iodophenyl)-4,5,6,7-tetrahydro...)
Affinity DataIC50:  800nMAssay Description:Inhibition of cathepsin S in human JY cells by invariant chain degradation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50152989(3-(5-carbamoyl-3-(4-iodophenyl)-4,5,6,7-tetrahydro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50152989(3-(5-carbamoyl-3-(4-iodophenyl)-4,5,6,7-tetrahydro...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed