BDBM50153111 CHEMBL189667::[(3S,5S,10S,13R,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yloxy]-acetic acid

SMILES CC(C)CCC[C@@H](C)[C@H]1CCC2C3CC[C@H]4C[C@H](CC[C@]4(C)C3CC[C@]12C)OCC(O)=O

InChI Key InChIKey=CUGYBEVFMLOOBH-VEABLZDGSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50153111   

TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center For Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153111(CHEMBL189667 | [(3S,5S,10S,13R,17R)-17-((R)-1,5-Di...)
Affinity DataKi:  7.84E+3nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center For Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153111(CHEMBL189667 | [(3S,5S,10S,13R,17R)-17-((R)-1,5-Di...)
Affinity DataKi:  1.38E+4nMAssay Description:Inhibition constant against DNA polymerase alpha competitively on DNA templateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Frontier Research Center For Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153111(CHEMBL189667 | [(3S,5S,10S,13R,17R)-17-((R)-1,5-Di...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitory concentration against rat DNA polymerase beta incubated with 0.05 unitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Frontier Research Center For Genome & Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50153111(CHEMBL189667 | [(3S,5S,10S,13R,17R)-17-((R)-1,5-Di...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory concentration against human DNA polymerase alpha incubated with 0.05 unitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed