BDBM50153172 6-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)methyl)-3'-(trifluoromethoxy)biphenyl-3-carbonitrile::6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethyl]-3''-trifluoromethoxy-biphenyl-3-carbonitrile::6-[3-(4-cyano-benzyl)-3H-imidazol-4-ylmethoxymethyl]-3'-trifluoromethoxy-biphenyl-3-carbonitrile::CHEMBL181748
SMILES FC(F)(F)Oc1cccc(c1)-c1cc(ccc1COCc1cncn1Cc1ccc(cc1)C#N)C#N
InChI Key InChIKey=IGCOPNHCHHWZNH-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50153172
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.370nMAssay Description:Inhibition of [3H]-FPP incorporation into recombinant Ras CVIM by human FarnesyltransferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.490nMAssay Description:Inhibition of bovine farnesyltransferaseMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Inhibition of bovine GeranylgeranyltransferaseMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Inhibition of [3H]-GGPP incorporation into C-terminus of K-Ras by human Geranylgeranyl transferase type IMore data for this Ligand-Target Pair