BDBM50153461 3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anilino-1H-pyrrole-2,5-dione::3-[1-(3-Imidazol-1-yl-propyl)-1H-indol-3-yl]-4-phenylamino-pyrrole-2,5-dione::CHEMBL366266

SMILES O=C1NC(=O)C(=C1Nc1ccccc1)c1cn(CCCn2ccnc2)c2ccccc12

InChI Key InChIKey=KIWODJBCHRADND-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50153461   

TargetProtein kinase C alpha type(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  331nMAssay Description:Inhibition of PKCalphaChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  331nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  2.81E+3nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C epsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  17nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  770nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PKCbetaChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PKCgammaChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of PKCepsilonChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50:  3.85E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed