BDBM50153652 CHEMBL3774985

SMILES CC(C)CCCc1nnc(CCC(=O)Nc2ccc(C)cc2C)n1C1CC1

InChI Key InChIKey=MOJJWCCZEAQHHZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153652   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153652(CHEMBL3774985)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of human RORgamma ligand binding domain (Serine 253 to Lysine 518 residues) expressed in CHOK1 cells incubated for 2 days by Gal4 lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153652(CHEMBL3774985)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of human GAL4-fused RORgamma LBD transcriptional activity expressed in CHOK1 cells after 2 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Mus musculus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153652(CHEMBL3774985)
Affinity DataEC50:  610nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed