BDBM50153786 4-((5-((4-cyanophenoxy)methyl)-1H-imidazol-1-yl)methyl)-2-(naphthalen-1-yl)benzonitrile::4-[5-(4-Cyano-phenoxymethyl)-imidazol-1-ylmethyl]-2-naphthalen-1-yl-benzonitrile::CHEMBL186617

SMILES N#Cc1ccc(OCc2cncn2Cc2ccc(C#N)c(c2)-c2cccc3ccccc23)cc1

InChI Key InChIKey=HMNKAAULLTXGJW-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153786   

TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50153786(4-((5-((4-cyanophenoxy)methyl)-1H-imidazol-1-yl)me...)Copy SMILESCopy InChI

Affinity DataIC50:  565nMAssay Description:Inhibition of bovine GeranylgeranyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50153786(4-((5-((4-cyanophenoxy)methyl)-1H-imidazol-1-yl)me...)Copy SMILESCopy InChI

Affinity DataIC50:  0.320nMAssay Description:Inhibition of bovine farnesyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI