BDBM50153870 CHEMBL184052::N-[3-(6,7-Dimethoxy-quinazolin-4-ylamino)-4-methyl-phenyl]-3-morpholin-4-yl-benzamide

SMILES COc1cc2ncnc(Nc3cc(NC(=O)c4cccc(c4)N4CCOCC4)ccc3C)c2cc1OC

InChI Key InChIKey=BLVTUXCPBJQIGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153870   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153870(CHEMBL184052 | N-[3-(6,7-Dimethoxy-quinazolin-4-yl...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibitory concentration against Epidermal growth factor receptor tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153870(CHEMBL184052 | N-[3-(6,7-Dimethoxy-quinazolin-4-yl...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against alpha mitogen activated protein kinase p38 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed