BDBM50153988 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-6-methoxy-pyrazolo[1,5-b]pyridazine::CHEMBL188115

SMILES COc1ccc2c(c(nn2n1)-c1ccc(F)cc1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=TZIFVBRWFVXOKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153988   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153988(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-6...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human cyclooxygenase-2 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50153988(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-6...)
Affinity DataIC50: >3.51E+4nMAssay Description:Inhibition of human cyclooxygenase-1 expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed