BDBM50154084 7-Bromo-2-(3-fluoro-4-hydroxy-phenyl)-benzooxazol-5-ol::7-bromo-2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol-5-ol::CHEMBL187207

SMILES Oc1cc(Br)c2oc(nc2c1)-c1ccc(O)c(F)c1

InChI Key InChIKey=GGHZQYDERZQJFP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50154084   

TargetEstrogen receptor beta(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154084(7-Bromo-2-(3-fluoro-4-hydroxy-phenyl)-benzooxazol-...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154084(7-Bromo-2-(3-fluoro-4-hydroxy-phenyl)-benzooxazol-...)
Affinity DataIC50:  199nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154084(7-Bromo-2-(3-fluoro-4-hydroxy-phenyl)-benzooxazol-...)
Affinity DataIC50:  260nMAssay Description:Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Yantai University

Curated by ChEMBL
LigandPNGBDBM50154084(7-Bromo-2-(3-fluoro-4-hydroxy-phenyl)-benzooxazol-...)
Affinity DataIC50:  3nMAssay Description:Binding affinity to ERbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Yantai University

Curated by ChEMBL
LigandPNGBDBM50154084(7-Bromo-2-(3-fluoro-4-hydroxy-phenyl)-benzooxazol-...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(RAT)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154084(7-Bromo-2-(3-fluoro-4-hydroxy-phenyl)-benzooxazol-...)
Affinity DataIC50:  171nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154084(7-Bromo-2-(3-fluoro-4-hydroxy-phenyl)-benzooxazol-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed