BDBM50154813 CHEMBL3774451

SMILES Fc1ccc(cc1)-n1nnc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c1C(F)(F)F

InChI Key InChIKey=ULHLSSWDQFLSBL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50154813   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Jiangxi Science And Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50154813(CHEMBL3774451)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of FLT3 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Jiangxi Science And Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50154813(CHEMBL3774451)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Jiangxi Science And Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50154813(CHEMBL3774451)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Jiangxi Science And Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50154813(CHEMBL3774451)
Affinity DataIC50:  325nMAssay Description:Inhibition of cKit (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangxi Science And Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50154813(CHEMBL3774451)
Affinity DataIC50:  582nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Jiangxi Science And Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50154813(CHEMBL3774451)
Affinity DataIC50:  86nMAssay Description:Inhibition of KDR (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed