BDBM50155166 4-(6-Chloro-pyridazin-3-yl)-piperazine-1-carboxylic acid (4-isopropyl-phenyl)-amide::CHEMBL363699

SMILES CC(C)c1ccc(NC(=O)N2CCN(CC2)c2ccc(Cl)nn2)cc1

InChI Key InChIKey=XSKDODVTPLNVBZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155166   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50155166(4-(6-Chloro-pyridazin-3-yl)-piperazine-1-carboxyli...)
Affinity DataIC50: >1.00E+4nMpH: 5.5Assay Description:Inhibition of human vanilloid receptor 1 in HEK293 cells in pH 5.5-induced FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPantothenate kinase 3(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50155166(4-(6-Chloro-pyridazin-3-yl)-piperazine-1-carboxyli...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50155166(4-(6-Chloro-pyridazin-3-yl)-piperazine-1-carboxyli...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human vanilloid receptor 1 in HEK293 cells in capsaicin-induced FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed