BDBM50155230 CHEMBL187903::N-(5-Cyclobutyl-thiazol-2-yl)-2-(5,6-dimethyl-benzoimidazol-1-yl)-acetamide

SMILES Cc1cc2ncn(CC(=O)Nc3ncc(s3)C3CCC3)c2cc1C

InChI Key InChIKey=BBSYDDJGTACDNC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155230   

TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155230(CHEMBL187903 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(5,...)
Affinity DataIC50:  13nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155230(CHEMBL187903 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(5,...)
Affinity DataIC50:  26nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed