BDBM50155568 1-(3-Diethylamino-phenyl)-3-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-urea::CHEMBL365673

SMILES CCN(CC)c1cccc(NC(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1

InChI Key InChIKey=YCDIUFZXJOHIGE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155568   

TargetBreakpoint cluster region protein(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155568(1-(3-Diethylamino-phenyl)-3-[4-methyl-3-(4-pyridin...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People'S Hospital Of Hangzhou

Curated by ChEMBL
LigandPNGBDBM50155568(1-(3-Diethylamino-phenyl)-3-[4-methyl-3-(4-pyridin...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155568(1-(3-Diethylamino-phenyl)-3-[4-methyl-3-(4-pyridin...)
Affinity DataIC50:  280nMAssay Description:Inhibitory concentration required to inhibit Abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed