BDBM50155612 5-Chloro-thiophene-2-carboxylic acid {(R)-3-methyl-1-[4-(2-oxo-2H-pyrazin-1-yl)-phenylcarbamoyl]-butyl}-amide::CHEMBL362110

SMILES CC(C)C[C@@H](NC(=O)c1ccc(Cl)s1)C(=O)Nc1ccc(cc1)-n1ccncc1=O

InChI Key InChIKey=HMIFPBWBFGURQV-MRXNPFEDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155612   

TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50155612(5-Chloro-thiophene-2-carboxylic acid {(R)-3-methyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human trypsin activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50155612(5-Chloro-thiophene-2-carboxylic acid {(R)-3-methyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human thrombin activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50155612(5-Chloro-thiophene-2-carboxylic acid {(R)-3-methyl...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibitory concentration against human serine protease factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed